Perioperative medicine & outcomes

The Efficacy of a Multidisciplinary Perianesthetic Management Bundle for Alleviating Delirium After Thoracic Surgery: A Randomized Clinical Trial

J Cardiothorac Vasc AnesthPublished Randomised controlled trial

Study context

Population
Patients scheduled for elective thoracic surgery with expected anaesthesia duration ≥2 hours, tertiary care university teaching hospital497 analysed
Participants
508 patients
Comparison
Intervention vs Control
  • Interventionn = 247
  • Controln = 250reference
Methodological detailsprospective, single-blind
  • Prospective
  • Single-blind

Primary result

As reported in the abstract

Postoperative delirium (Confusion Assessment Method)
Bundle perianesthetic management, lower risk of delirium, per-protocol analysis: RR
0.40 (95% CI 0.19-0.84, p = 0.012)
Bundle perianesthetic management, lower risk of delirium, ITT analysis: RR
0.39 (95% CI 0.19-0.84, p = 0.011)

Further findings

Delirium duration, postoperative pain, activities of daily living, hospital LOS, hospital-related costs

No significant differences between the groups

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

The Efficacy of a Multidisciplinary Perianesthetic Management Bundle for Alleviating Delirium After Thoracic Surgery: A Randomized Clinical Trial. J Cardiothorac Vasc Anesth. Published 22 October 2025. doi:10.1053/j.jvca.2025.10.025

Composed by AI from the published abstract and checked against it. How Briefs are made →

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