Perioperative medicine & outcomes
The impact of substance use disorders on postoperative falls in major noncardiac surgery: A retrospective cohort analysis
Main finding · Postoperative fall, matched cohortResult — go to the resultOdds ratio 1.71 95 % CI 1.06–2.75Authors' conclusion
Patients with a substance use disorder had increased risks of postoperative falls.
Study context
- Population
- Adults (≥18 years) undergoing major elective noncardiac surgery, New York State Inpatient and ED Databases, 2016 to 20192.12 % with active substance use disorder
- Participants
- 365,797 adults
- Exposure
- Substance use disorder vs no substance use disorder
- Outcome
- Postoperative fall (in-hospital fall after surgery, or ED visit for a fall within 30-days of surgical discharge)
Methodological detailspropensity-score matched
- Propensity-score matched
Main finding
Postoperative fall, matched cohort · 30-days
Odds ratio
1.71
95 % CI 1.06–2.75
P = 0.028
Substance use disorder vs No substance use disorder
OR 1.71 (95 % CI 1.06–2.75); P = 0.028
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Crude odds (95 % CI) | P value |
|---|---|---|
| Postoperative fall, unmatched cohort (crude)Unmatched cohort | 2.08 (1.55–2.80) | P < 0.001 |
Original publication
The impact of substance use disorders on postoperative falls in major noncardiac surgery: A retrospective cohort analysis. J Clin Anesth. Published 21 March 2025. doi:10. 1016/ j. jclinane. 2025. 111814
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