ICU sedation, delirium & recovery

The intensive care medicine research agenda for the management of ICU acquired weakness: a multinational, interprofessional perspective

Intensive Care MedPublished Research agenda

Methodological detailsexpert consensus statement, systematic review with meta-analysis, two expert panel meetings, two-round modified Delphi method, multinational, interprofessional
  • Expert consensus statement
  • Systematic review with meta-analysis
  • Two expert panel meetings
  • Two-round modified Delphi method
  • Multinational
  • Interprofessional

Recommendations

As issued by the authors

  1. Focus future research on early prognostic markers, mechanisms of intensive care unit acquired weakness (ICUAW), and identification of treatment responders allowing individualised dosing across the recovery trajectory

  2. Define meaningful outcomes, improve follow-up care, and integrate patient, family and caregiver priorities

  3. Interdisciplinary collaboration and emerging methods, including artificial intelligence, to support personalised ICUAW care

Original publication

The intensive care medicine research agenda for the management of ICU acquired weakness: a multinational, interprofessional perspective. Intensive Care Med. Published 3 November 2025. doi:10.1007/s00134-025-08186-4

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