Cardiac arrest & resuscitation
The link between carotid artery stenosis and outcomes in patients with refractory out-of-hospital cardiac arrest
Authors' conclusion
CAS burden independently predicts the risk for worse survival and neurologic outcomes in patients suffering refractory OHCA who are treated with ECPR.
Study context
- Population
- Patients with refractory out-of-hospital cardiac arrest (OHCA) admitted for extracorporeal cardiopulmonary resuscitation (ECPR) consideration who had carotid ultrasonography, 2019–2023
- Participants
- 163 patients
- Exposure
- Degrees of carotid artery stenosis (CAS) burden
- Outcome
- Survival at discharge, compared among degrees of CAS
- Follow-up
- Discharge
Main finding
As reported in the abstract
Overall and neurologically intact survival at discharge
- CAS burden significantly associated with overall and neurologically intact survival at discharge (logistic regression)
- p = 0.004
Observational data: associations, not effects.
Further findings
Neuron-specific and S-100 levels
- Linear relationship between CAS burden and neuron-specific and S-100 levels
Encephalopathy on EEG
- Patients with normal carotids significantly less likely to have encephalopathy
Original publication
The link between carotid artery stenosis and outcomes in patients with refractory out-of-hospital cardiac arrest. Resuscitation. Published 20 June 2024. doi:10.
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