Neuroanesthesia & neurocritical care
The Long-Term Use of Diagnostic Subdural Electroencephalogram Electrodes and Subdural Hematoma: A Prospective Cohort Study*
- Trial stopped after a study committee meeting when prespecified criteria were met
Authors' conclusion
Invasive subdural electroencephalogram monitoring is valuable and safe for early seizure/SE detection and treatment and might improve outcomes in the neurocritical care of patients with aSDH.
Study context
- Population
- Patients with acute subdural hematoma (aSDH) undergoing surgical treatment, neurologic and neurosurgical ICUs of one academic hospital in Germany
- Participants
- 76 patients
- Exposure
- Invasive subdural EEG monitoring vs regular surface EEG
- Invasive electroencephalogram (iEEG)n = 31
- Controln = 45reference
- Outcome
- Prevalence and time to seizures and SE occurrence
Methodological detailssingle-center, stopped when prespecified criteria were met
- Single-center
- Stopped when prespecified criteria were met
Main finding
As reported in the abstract
Seizure and SE detection
Seizure and SE detection
SE detection
Time to seizure detection, median iEEG 29.2 hr · Control 83.8 hr
Time to SE detection, median iEEG 17.2 hr · Control 83.8 hr
- iEEG vs Control: P < 0.001
- iEEG vs Control: P = 0.005
- iEEG vs Control: P = 0.018 — significantly earlier in iEEG
- iEEG vs Control: P = 0.033 — significantly earlier in iEEG
Observational data: associations, not effects.
Secondary outcomes
Favorable outcome (GOS 4-5)
P = 0.065
Long-term mortality and post-traumatic epilepsy
- No significant differences
Original publication
The Long-Term Use of Diagnostic Subdural Electroencephalogram Electrodes and Subdural Hematoma: A Prospective Cohort Study*. Crit Care Med. Published 28 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →