Perioperative medicine & outcomes

The Number Needed to Treat for Music as a Medicine against Perioperative Anxiety: A Systematic Review and Meta-Analysis

Anesth AnalgPublished Systematic review and meta-analysis of randomised trials

Pooled result · Anxiety reduction after music interventionsResult — go to the resultSMD −0.72 95% CI −0.92 to −0.53

Authors' conclusion

This meta-analysis shows that a relatively low number of patients need to be treated with music intervention to reduce perioperative anxiety with an effectiveness similar to benzodiazepines.

Study context

Population
Surgical patients with perioperative anxiety (RCTs)20 papers
Comparison
Perioperative music intervention vs control
Outcome
Perioperative anxiety (VAS for Anxiety or 6-item State-Trait Anxiety Index); NNT
Methodological detailsCochrane risk-of-bias assessment, NNT by Furukawa's method
  • Cochrane risk-of-bias assessment
  • NNT by Furukawa's method

Pooled result

Anxiety reduction after music interventions

SMD

−0.72

95% CI −0.92 to −0.53

Music vs Control
SMD −0.72 (95% CI −0.92 to −0.53)

As reported in the abstract

NNT for perioperative music intervention
4

Original publication

The Number Needed to Treat for Music as a Medicine against Perioperative Anxiety: A Systematic Review and Meta-Analysis. Anesth Analg. Published 13 March 2026. doi:10.1213/ane.0000000000007815

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