Cardiac arrest & resuscitation

The post-ROSC ECG: morphological spectrum of non-ST-elevation occlusion and prognostic markers after cardiac arrest

ResuscitationPublished Retrospective cohort study

Authors' conclusion

On the first post-ROSC ECG, angiographically confirmed occlusion concentrated around a small number of NST-OMI morphologies - findings of crucial importance for identification and appropriate management. PR-segment prolongation predicted reduced 30-day survival - indicating prognostic information beyond ischaemia detection.

Study context

Population
Cardiac arrest survivors admitted to a tertiary ICU (2020–2025), first post-ROSC ECG; Coronary angiography (CAG) as reference standard for occlusive myocardial infarction (OMI)101 CAG-confirmed OMI
Participants
214 survivors
Exposure
NST-OMI vs STEMI patterns on first post-ROSC ECG; ECG features in non-survivors vs survivors
Outcome
Distribution of NST-OMI patterns post-ROSC; association of quantitative ECG features with survival
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

NST-OMI patterns among CAG-confirmed OMI
Left-main equivalent
8%
Smith-modified Sgarbossa criteria
8%
Aslanger pattern
5%
Lateral OMI
4%
Shark-fin sign
4%
Hyperacute t-wave
4%

Observational data: associations, not effects.

Further findings

Prevalence of pattern, overall

Prevalence of pattern among CAG-confirmed OMI

Underwent CAG

P = 0.002

PR-segment prolongation and 30-day survival (multivariable)

aOR (CI)P value
PR-segment prolongationIndependently associated with reduced 30-day survival0.977 (0.956–0.998)P = 0.032
OutcomeP value
PR-segment, non-survivors vs survivorsP = 0.008
QRS-duration, non-survivors vs survivorsP = 0.003
P-wave duration, non-survivors vs survivorsP = 0.027
  • PR-segment, non-survivors vs survivors: Non-survivors 74 ms
  • PR-segment, non-survivors vs survivors: Survivors 57 ms
  • QRS-duration, non-survivors vs survivors: Non-survivors 130 ms
  • QRS-duration, non-survivors vs survivors: Survivors 108 ms
  • P-wave duration, non-survivors vs survivors: Non-survivors 105 ms
  • P-wave duration, non-survivors vs survivors: Survivors 108 ms

Mortality, NST-OMI without CAG · 30 days

Highest 30-day mortality among NST-OMI patients not undergoing CAG
75%
  • p = 0.005

Original publication

The post-ROSC ECG: morphological spectrum of non-ST-elevation occlusion and prognostic markers after cardiac arrest. Resuscitation. Published 25 September 2026. doi:10.1016/j.resuscitation.2026.111334

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