Cardiac arrest & resuscitation
The prognostic role of cerebral ultrasound in hypoxic-ischemic encephalopathy: A systematic review
Authors' conclusion
The role of cerebral ultrasound in prognostication after OHCA has been poorly described.
Study context
- Population
- Adults after out-of-hospital cardiac arrest (OHCA) (hypoxic-ischemic encephalopathy) assessed by cerebral ultrasound for neuroprognostication14 studies
- Outcome
- Unfavourable outcome (UO), per individual study criteria, predicted by cerebral ultrasound (CBFV, ONSD, CVR)
Pooled result
As reported in the abstract
Optic nerve sheath diameter (ONSD) associated with unfavourable outcome (UO) in 5 of 6 studies; cutoffs between 5.3 and 7.2 mm
5.3–7.2 mm
Original publication
The prognostic role of cerebral ultrasound in hypoxic-ischemic encephalopathy: A systematic review. Resuscitation. Published 21 October 2025. doi:10.
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