Cardiac arrest & resuscitation
Toxicological profile using mass spectrometry in sudden cardiac arrest survivors admitted to a tertiary centre
Authors' conclusion
In resuscitated sudden cardiac arrest patients with cardiac arrest of presumed cardiac cause, routine toxicological screening provides limited extra information.
Study context
- Population
- Adults aged 18–90 years resuscitated from sudden cardiac arrest of presumed cardiac cause, single tertiary centre
- Participants
- 186 adults
- Outcome
- Qualitative and quantitative drug composition by mass spectrometry-based forensic toxicology
Methodological detailssingle-centre, consecutive enrolment
- Single-centre
- Consecutive enrolment
Main finding
As reported in the abstract
Drug detection by toxicology
- Different drugs identified (excluding metabolites)
- 90
- Patients with ≥1 drug detected
- 82%
- Detected drugs per patient, median (IQR)
- 2 (1-4)
- Commonly abused drugs present
- 16%
- QT-prolonging drugs present
- 12%
- Polypharmacy (≥5 drugs)
- 19%
- Potentially lethal drug concentrations
- 0
Observational data: associations, not effects.
Original publication
Toxicological profile using mass spectrometry in sudden cardiac arrest survivors admitted to a tertiary centre. Resuscitation. Published 4 April 2024. doi:10.
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