Transcutaneous carbon dioxide monitoring during prolonged apnoea with high‐flow nasal oxygen
Authors' conclusion
Transcutaneous carbon dioxide monitoring provided a clinically acceptable substitute for arterial blood gases but as hypercapnia developed to considerable levels, we observed overestimation at high carbon dioxide tensions in patients undergoing apnoeic oxygenation with high-flow nasal oxygen.
Study context
- Population
- Anaesthetised and paralysed patients undergoing prolonged apnoeic oxygenation with HFNO until pH 7.15 or PCO2 12 kPa
- Participants
- 35 participants
- Comparison
- Transcutaneous CO2 monitoring vs arterial CO2 tension
- Primary endpoint
- Agreement of transcutaneous CO2 with arterial CO2 tension (Bland-Altman)
Methodological detailssecondary analysis of a study of prolonged apnoeic oxygenation, Bland-Altman analysis
- Secondary analysis of a study of prolonged apnoeic oxygenation
- Bland-Altman analysis
Primary result
As reported in the abstract
Agreement of transcutaneous vs arterial CO2
Bias range
−0.55 to 0.81 kPa
Limits of agreement
between −1.25 and 2.11 kPa
Further findings
Apnoea duration and blood gases at termination of apnoeic oxygenation
- Median apnoea duration
- 25 min
- Mean pH
- 7.14
- Mean arterial CO2 tension
- 11.2 kPa
Original publication
Transcutaneous carbon dioxide monitoring during prolonged apnoea with high‐flow nasal oxygen. Acta Anaesthesiol Scand. Published 19 February 2023. doi:10.
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