Transfusion and bleeding risk associated with terbutaline administration for external cephalic version among patients delivering the same day: a retrospective cohort study using the Premier Healthcare Database (2016–2020)
Authors' conclusion
Terbutaline for tocolysis in the context of external cephalic version was not associated with increased incidence of blood transfusion or postpartum hemorrhage, irrespective of delivery mode.
Study context
- Population
- Singleton pregnancies with an external cephalic version on the date of delivery, 2016–202026.3% received terbutaline
- Participants
- 9,030 pregnancies
- Exposure
- Terbutaline vs no terbutaline for external cephalic version
- Outcome
- Need for blood transfusion and postpartum hemorrhage incidence
Methodological detailsPremier Healthcare Database
- Premier Healthcare Database
Main finding
As reported in the abstract
Postpartum hemorrhage and blood transfusion
- Lower overall incidence of postpartum hemorrhage with terbutaline vs no terbutaline
- No adjustment for confounding factors
Observational data: associations, not effects.
Further findings
Postpartum hemorrhage and blood transfusion by route of delivery (subgroup)
- Postpartum hemorrhage lower with terbutaline in spontaneous vaginal delivery; no other statistically significant differences in blood transfusion or postpartum hemorrhage
Original publication
Transfusion and bleeding risk associated with terbutaline administration for external cephalic version among patients delivering the same day: a retrospective cohort study using the Premier Healthcare Database (2016–2020). Int J Obstet Anesth. Published 6 June 2026. doi:10.
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