Neuroanesthesia & neurocritical care
Traumatic cervical spinal cord injury: Comparison of two different blood pressure targets on neurological recovery
Authors' conclusion
The currently recommended MAP target of 85-90 mmHg was not associated with improved outcomes compared to a lower target in patients with traumatic cervical SCI in this cohort.
Study context
- Population
- Adults with traumatic cervical spinal cord injury (SCI)
- Participants
- 51 adults
- Exposure
- Mean arterial pressure (MAP) target 85-90 mmHg vs 65-85 mmHg in the intensive care unit (ICU)
- Higher MAPn = 32
- Lower MAPn = 19reference
- Outcome
- Neurological recovery (AIS grade and neurological level)
Main finding
As reported in the abstract
Neurological recovery
- Neurological recovery not different between the groups, nor correlated with individual mean MAP values or 3d-MAP%≥85
Observational data: associations, not effects.
Further findings
Measured MAP values ≥85 mmHg during ICU care
P < 0.001
AIS grade improvement, all patients
- AIS grade improved
- 24 (47.1%)
Individual mean MAP values (medians)
- Medians of individual mean MAP differed between the groups (p < .001)
- 90.2 mmHg vs. 81.4 mmHg
Proportion of MAP values ≥85 mmHg over the first 3 days (3d-MAP%≥85)
- 3d-MAP%≥85 higher in the higher MAP group (p < .001)
- 85.6% vs. 50.0%
Original publication
Traumatic cervical spinal cord injury: Comparison of two different blood pressure targets on neurological recovery. Acta Anaesthesiol Scand. Published 16 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →