Emergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta in Trauma Patients With Exsanguinating Hemorrhage: The UK-REBOA Randomized Clinical Trial
Primary resultResult — go to the resultOdds ratio 1.58 95% CrI 0.72–3.52Authors' conclusion
In trauma patients with exsanguinating hemorrhage, a strategy of REBOA and standard care in the emergency department does not reduce, and may increase, mortality compared with standard care alone.
Study context
- Population
- Trauma patients aged 16 years or older with exsanguinating hemorrhage, 16 major trauma centers in the UK89 in primary analysis
- Participants
- 90 patients
- Comparison
- Resuscitative endovascular balloon occlusion of the aorta (REBOA) in the ED plus standard care vs standard care alone
- REBOA and standard caren = 46
- Standard care alonen = 44reference
- Primary endpoint
- All-cause mortality
- Follow-up
- 90 days
Methodological detailspragmatic, bayesian, multicentre
- Pragmatic
- Bayesian
- Multicentre
Primary result
As reported in the abstract
Odds ratio
1.58
95% CrI 0.72–3.52
Events by treatment group
REBOA and standard care vs Standard care alone
OR 1.58 (95% CrI 0.72–3.52)
Secondary outcomes
Deaths due to bleeding (of deaths)
Mortality at 6 months, in hospital, and within 24, 6 or 3 hours
- ORs and posterior probabilities of OR >1 all increased in the REBOA and standard care group; ORs increased with earlier mortality end points
Deaths due to bleeding (of deaths)
- Most deaths due to bleeding occurred within 24 hours
Original publication
Emergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta in Trauma Patients With Exsanguinating Hemorrhage: The UK-REBOA Randomized Clinical Trial. JAMA. Published 21 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →