Perioperative medicine & outcomes
An Updated Systematic Review and Meta-analysis of the Impact of Graduated Compression Stockings in Addition to Pharmacological Thromboprophylaxis for Prevention of Venous Thromboembolism in Surgical Inpatients
Pooled result · DVT (head-to-head meta-analysis)Result — go to the resultrisk 0.85 95% CI 0.54–1.36Authors' conclusion
Evidence from head-to-head meta-analysis and pooled trial arms demonstrates no additional benefit for GCS in preventing VTE and VTE-related mortality.
Study context
- Population
- Surgical inpatients
- Comparison
- GCS plus pharmacological thromboprophylaxis vs pharmacological thromboprophylaxis alone
- Outcome
- VTE rate (deep venous thrombosis (DVT), PE, VTE-related mortality)
Methodological detailshead-to-head meta-analysis, pooled trial arms, fixed and random effects, MEDLINE and Embase searched up to November 2022
- Head-to-head meta-analysis
- Pooled trial arms
- Fixed and random effects
- MEDLINE and Embase searched up to November 2022
Pooled result
DVT (head-to-head meta-analysis)
risk
0.85
95% CI 0.54–1.36
As reported in the abstract
Further pooled results
| Outcome | Risk (95% CI) |
|---|---|
| DVT (pooled trial arms)33 trial arms, 1228 events, 14,108 participants | 0.54 (0.23–1.25) |
| PE27 trial arms, 32 events, 11,472 participants | 0.71 (0.0–30.0) |
Venous thromboembolism (VTE)-related mortality
- No between-group differences (27 trial arms, 3 events, 12,982 participants)
Original publication
An Updated Systematic Review and Meta-analysis of the Impact of Graduated Compression Stockings in Addition to Pharmacological Thromboprophylaxis for Prevention of Venous Thromboembolism in Surgical Inpatients. Ann Surg. Published 27 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →