Use of Continuous Regional Anesthesia Infusion as an Opioid‐Sparing Modality in Mechanically Ventilated Patients With Acute Traumatic Rib Fractures—A Retrospective Study
Authors' conclusion
CRA use was associated with a decrease in opioid consumption 24-48 h after CRA intervention compared to baseline. CRA did not facilitate early liberation from MV.
Study context
- Population
- Mechanically ventilated patients with acute traumatic rib fractures referred to the Acute Pain Service (January 2022-July 2023)
- Participants
- 40 participants
- Exposure
- Continuous Regional Anesthesia (CRA) vs no CRA at Acute Pain Service consultation
- CRAn = 22
- non-CRAn = 18reference
- Outcome
- Opioid consumption (oral morphine equivalents) and rate of liberation from MV
- Follow-up
- 0-48 h post-intervention
Main finding
As reported in the abstract
Opioid consumption (oral morphine equivalents) · 0-24 h post-intervention
CRA
135
median · range 33.1–296.6 · mg
non-CRA
368.3
range 121.5–727.9
P = 0.018
Observational data: associations, not effects.
Further findings
| Outcome | CRA | non-CRA | P value |
|---|---|---|---|
| Opioid consumption (oral morphine equivalents) · 24-48 h post-intervention | 31.5 (range 11.5–131.6) mg | 342.8 (range 99.3–645.8) | P = 0.001 |
Rate of liberation from mechanical ventilation (MV)
- No significant difference between groups
Original publication
Use of Continuous Regional Anesthesia Infusion as an Opioid‐Sparing Modality in Mechanically Ventilated Patients With Acute Traumatic Rib Fractures—A Retrospective Study. Acta Anaesthesiol Scand. Published 27 October 2025. doi:10.
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