Perioperative medicine & outcomes

Using inability to walk to predict in-hospital mortality in a high-income country – A comparison with the National Early Warning Score in a multicenter prospective cohort

J Crit CarePublished Prospective cohort study

Authors' conclusion

Inability to walk (IATW) is a bedside assessment that when negative identifies patients with low 30-day in-hospital mortality and provides complementary information to NEWS.

Study context

Population
All adult inpatients in four Swedish hospitals
Participants
1,842 inpatients
Exposure
Inability to walk (IATW) vs NEWS CRITICAL
Outcome
30-day in-hospital mortality
Follow-up
30 days
Methodological detailsmulticentre, point-prevalence assessment, diagnostic accuracy
  • Multicentre
  • Point-prevalence assessment
  • Diagnostic accuracy

Main finding

As reported in the abstract

Predictive accuracy for 30-day in-hospital mortality
GroupSensitivitySpecificityNPVPositive
IATW86.9%41.4%98.5%59.9%
NEWS CRITICAL66.7%79.8%98.0%22.3%

Sensitivity

IATW86.9%
NEWS CRITICAL66.7%

Specificity

IATW41.4%
NEWS CRITICAL79.8%

NPV

IATW98.5%
NEWS CRITICAL98.0%

Positive

IATW59.9%
NEWS CRITICAL22.3%
Overall mortality
4.6%

Observational data: associations, not effects.

Further findings

OutcomeOR (95% CI)P value
Association of IATW with mortality, adjusted for NEWS, age and sexMultivariable logistic regression2.43 (1.24–4.76)P = 0.009

Mortality in IATW-negative with NEWS <5

Mortality (35.2% of cohort)
1.1%

Original publication

Using inability to walk to predict in-hospital mortality in a high-income country – A comparison with the National Early Warning Score in a multicenter prospective cohort. J Crit Care. Published 26 April 2026. doi:10.1016/j.jcrc.2026.155598

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