ICU sedation, delirium & recovery
A first‐level customization study of SAPS II with Norwegian Intensive Care and Pandemic Registry (NIPaR) data
Authors' conclusion
The observed mortality and corresponding SAPS II scores have significantly changed during the last decades and an updated MPM is superior to the original SAPS II.
Study context
- Population
- Intensive care unit (ICU) patients in the Norwegian Intensive Care and Pandemic Registry (NIPaR), 2018 to 2020, COVID patients omitted2,018–2020 registry patients
- Participants
- 43,891 patients
- Exposure
- Customized SAPS II Model C vs original SAPS II (Model A) and NIPaR 2008–2010 SAPS II (Model B)
- Outcome
- Model performance: calibration, discrimination and uniformity of fit (mortality prediction)
Methodological detailsfirst-level customization, national registry
- First-level customization
- National registry
Main finding
As reported in the abstract
Calibration (Brier score)
Model A
0.143
Brier score · 95% CI 0.141–0.146
Model B
0.133
Brier score · 95% CI 0.130–0.135
Model C
0.132
Brier score · 95% CI 0.130–0.135
Observational data: associations, not effects.
Further findings
Uniformity of fit
- Similar for Model B and Model C, both better than Model A, across age groups, sex, LOS, type of admission, hospital category and days on respirator
Discrimination (area under the ROC curve)
- AUC, acceptable discrimination
- 0.79 (95% CI 0.79-0.80)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
A first‐level customization study of SAPS II with Norwegian Intensive Care and Pandemic Registry (NIPaR) data. Acta Anaesthesiol Scand. Published 17 March 2023. doi:10.
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