ICU sedation, delirium & recovery
Definitions, epidemiology, and outcomes of persistent/chronic critical illness: a scoping review for translation to clinical practice
Authors' conclusion
This scoping review synthesized many studies on PerCI/CCI, highlighting the serious impact of PerCI/CCI on patients' long-term outcomes.
Study context
- Population
- Adults with persistent critical illness (PerCI) or chronic critical illness (CCI); peer-reviewed original research published until May 31, 2024 (MEDLINE, Scopus)99 studies
- Outcome
- Definitions, epidemiology and outcomes of PerCI/CCI
Methodological detailsPRISMA-ScR
- PRISMA-ScR
Pooled result
As reported in the abstract
Prevalence of PerCI/CCI
- Prevalence among all ICU patients
- 11% (95% CI 10-12%)
- Prevalence in sepsis
- 28% (22-34%)
- Prevalence in trauma
- 24% (15-33%)
- Prevalence in COVID-19
- 35% (20-50%)
- Prevalence of CCI
- 17% (16-18%)
- Prevalence of PerCI
- 18% (16-20%)
Further pooled results
Mortality of PerCI/CCI
- In-hospital mortality
- 27% (26-29%)
- One-year mortality
- 45% (32-58%)
- In-hospital mortality, CCI
- 28% (26-30%)
- In-hospital mortality, PerCI
- 26% (24-29%)
Functional outcomes
- Generally poor, with many survivors requiring long-term care
Original publication
Definitions, epidemiology, and outcomes of persistent/chronic critical illness: a scoping review for translation to clinical practice. Crit Care. Published 28 December 2024. doi:10.
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