Respiratory failure & ventilation
A new reservoir-based continuous positive airway pressure (CPAP) with low oxygen consumption: the Bag-CPAP
Authors' conclusion
In vitro, Bag-CPAP exhibited the highest oxygen saving properties albeit had increased WOB. It was well accepted clinically and reduced dyspnea.
Study context
- Population
- Adults with acute respiratory failure in two hospitals in France (clinical part); bench testing of CPAP devicesclinical study
- Participants
- 20 adults
- Exposure
- Bag-CPAP vs four CPAP devices and an ICU ventilator
- Bag-CPAPn = 20
- Outcome
- Delivered FiO2 and oxygen consumption (bench); device-imposed WOB
Methodological detailsbench study and observational clinical study, two hospitals
- Bench study and observational clinical study
- Two hospitals
Main finding
As reported in the abstract
Bench performance
- All six systems reached the minimal fraction of inspired oxygen (FiO2) target of 40%; four reached ≥80% FiO2 with positive end expiratory pressure (PEEP) in range
- Device-delivered FiO2/consumed oxygen ratio highest with Bag-CPAP irrespective of FiO2 target
Observational data: associations, not effects.
Further findings
- Clinical study: oxygen flow rate to reach high (>90%) and moderate (>50%) FiO2 with Bag-CPAP — Bag-CPAP
- 15 (IQR 15–16) L/min
- Clinical study: oxygen flow rate to reach high (>90%) and moderate (>50%) FiO2 with Bag-CPAP: Bag-CPAP 8 (IQR 7–9) L/min
- Clinical study: oxygen flow rate to reach high (>90%) and moderate (>50%) FiO2 with Bag-CPAP: 15 [15-16] L/min for FiO2 > 90%; 8 [7-9] L/min for FiO2 > 50%
Clinical study: dyspnea score and SpO2
- Dyspnea score improved significantly after introduction of Bag-CPAP, and SpO2 increased
Safety
Device-imposed work of breathing (WOB) (bench) and tolerance (clinical)
- WOB induced by the device higher with Bag-CPAP
- Bag-CPAP well tolerated clinically
Original publication
A new reservoir-based CPAP with low oxygen consumption: the Bag-CPAP. Crit Care. Published 4 July 2023. doi:10.
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