ICU sedation, delirium & recovery

A randomized clinical trial to evaluate the effect of post-intensive care multidisciplinary consultations on mortality and the quality of life at 1 year

Intensive Care MedPublished Randomised controlled trial

Primary resultResult — go to the resultAdjusted odds ratio 1.49 95% CI 1.04–2.13

Authors' conclusion

A hospital-based, face-to-face, intensivist-led multidisciplinary consultation at ICU discharge then at 3 and 6 months was associated with poor outcome 1 year after ICU.

Study context

Population
Patients discharged alive from intensive care unit (ICU) in 11 French hospitals, 2012–2018
Participants
540 patients
Comparison
Post-ICU multidisciplinary consultations vs standard post-ICU follow-up
  • Multidisciplinaryn = 268
  • Standardn = 272reference
Primary endpoint
Poor clinical outcome: death or severe-to-extreme impairment of ≥1 EuroQoL-5D-5L dimension
Follow-up
M12
Methodological detailsopen, multicentre, parallel-group, Blinded investigator collected outcome by phone
  • Open
  • Multicentre
  • Parallel-group
  • Blinded investigator collected outcome by phone

Primary result

As reported in the abstract

Adjusted odds ratio

1.49

95% CI 1.04–2.13

Multidisciplinary vs Standard
aOR 1.49 (95% CI 1.04–2.13)

Secondary outcomes

Events

OutcomeMultidisciplinaryStandard
Death · M124032
Death — Total deaths
72 (13.3%)

Functional, psychological and cognitive scores · M12

Did not statistically differ between groups

Original publication

A randomized clinical trial to evaluate the effect of post-intensive care multidisciplinary consultations on mortality and the quality of life at 1 year. Intensive Care Med. Published 8 April 2024. doi:10.1007/s00134-024-07359-x

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