Regional anesthesia

A Randomized Controlled Trial of Adding Deep Parasternal Intercostal Plane Block to Interpectoral-Pectoserratus Plane Block in Breast Cancer Surgery

Anesth AnalgPublished Randomised controlled trial

Primary resultResult — go to the resultMean difference 0.4 95% CI −2.0 to 2.9

Authors' conclusion

Addition of deep parasternal intercostal plane block was not superior to interpectoral-pectoserratus plane block alone for the quality of recovery in patients undergoing breast cancer surgery.

Study context

Population
Patients undergoing breast cancer surgery
Participants
116 patients
Comparison
Single block vs Combined block
  • Single blockn = 58reference
  • Combined blockn = 58
Primary endpoint
QoR-15 questionnaire score
Follow-up
24 hours postoperatively

Primary result

As reported in the abstract

Mean difference

0.4

95% CI −2.0 to 2.9

P = 0.731

By group

Single block

123.6

mean · SD 6.3

Combined block

123.2

mean · SD 7.1

Single block vs Combined block
mean difference 0.4 (95% CI −2.0 to 2.9); P = 0.731

Secondary outcomes

Dermatomal block on medial breast

Greater dermatomal block on medial breast in the combined block group

Pain severity, opioid consumption, hospital LOS, chronic postsurgical pain at 3 months

No differences in other secondary outcomes

Original publication

A Randomized Controlled Trial of Adding Deep Parasternal Intercostal Plane Block to Interpectoral-Pectoserratus Plane Block in Breast Cancer Surgery. Anesth Analg. Published 1 May 2025. doi:10.1213/ane.0000000000007218

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