Infiltration between the popliteal artery and the capsule of the knee ( IPACK ) vs. selective tibial nerve block for analgesia after total knee arthroplasty: a triple‐blinded randomised controlled trial
Authors' conclusion
The IPACK and selective tibial nerve block provide similar analgesia after total knee arthroplasty under spinal anaesthesia with a femoral triangle block.
Study context
- Population
- Patients having total knee arthroplasty under spinal anaesthesia with a femoral triangle blockpatients whose data were analysed
- Participants
- 90 patients
- Comparison
- IPACK vs selective tibial nerve block
- IPACKn = 45
- Selective tibial nerve blockn = 45
- Primary endpoint
- Cumulative intravenous morphine consumption
- Follow-up
- Postoperative day 1
Primary result
As reported in the abstract
P = 0.36
Secondary outcomes
Secondary outcomes (pain scores at rest and during movement, quadriceps strength, walking distance, range of motion)
- No other differences were seen between groups in secondary outcomes
Safety
| Outcome | Selective tibial nerve block |
|---|---|
| Motor block of the common peroneal nerve | 9% |
Original publication
Infiltration between the popliteal artery and the capsule of the knee ( IPACK ) vs. selective tibial nerve block for analgesia after total knee arthroplasty: a triple‐blinded randomised controlled trial. Anaesthesia. Published 18 October 2026. doi:10.
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