Regional anesthesia

Analgesic efficacy of selective tibial nerve block versus partial local infiltration analgesia for posterior pain after total knee arthroplasty: a randomized, controlled, triple-blinded trial

Anaesth Crit Care Pain MedPublished Randomised controlled trial

Authors' conclusion

A tibial nerve block does not provide superior analgesia when compared to infiltration. However, a tibial nerve block might be associated with a slower increase in morphine consumption over time.

Study context

Population
Patients scheduled for total knee arthroplasty under spinal anesthesia with an adductor canal block
Participants
60 patients
Comparison
Tibial nerve block vs Infiltration
Primary endpoint
IV morphine consumption
Follow-up
24 h
Methodological detailstriple-blinded, sham injections
  • Triple-blinded
  • Sham injections

Primary result

As reported in the abstract

Cumulative IV morphine consumption

P = 0.20

Secondary outcomes

Morphine consumption over time (longitudinal mixed-effects model) · up to 48 h

Significant group × time interaction in favor of the tibial nerve block
  • Interaction p = 0.015

Pain scores at rest and on movement, functional outcomes · up to 48 h

No significant differences between groups

Original publication

Analgesic efficacy of selective tibial nerve block versus partial local infiltration analgesia for posterior pain after total knee arthroplasty: a randomized, controlled, triple-blinded trial. Anaesth Crit Care Pain Med. Published 6 April 2023. doi:10.1016/j.accpm.2023.101223

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