Regional anaesthesia

Infiltration between the popliteal artery and the capsule of the knee ( IPACK ) vs. selective tibial nerve block for analgesia after anterior cruciate ligament reconstruction: a randomised controlled trial

AnaesthesiaPublished randomised controlled triple-blinded trial

Authors' conclusion

The IPACK and selective tibial nerve block provide comparable postoperative analgesia after anterior cruciate ligament reconstruction under general anaesthesia with a femoral triangle block, with similar impact on functional outcomes.

Study context

Population
Patients having anterior cruciate ligament reconstruction under general anaesthesia with a femoral triangle blockallocated randomly
Participants
Eighty patients
Comparison
IPACK provides superior analgesia to a selective tibial nerve block after anterior cruciate ligament reconstruction
Primary endpoint
Cumulative postoperative intravenous morphine consumption
Follow-up
24 h

Primary result

As reported in the abstract

P = 0.073

Further findings

Secondary pain and functional outcomes

No significant differences between groups

Safety

No complications were reported

Original publication

Infiltration between the popliteal artery and the capsule of the knee ( IPACK ) vs. selective tibial nerve block for analgesia after anterior cruciate ligament reconstruction: a randomised controlled trial. Anaesthesia. Published 6 October 2026. doi:10.1111/anae.70433

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