Perioperative medicine & outcomes
Comparison of femoral triangle plus iPACK blocks with femoral triangle block alone for anterior cruciate ligament reconstruction: a randomized controlled clinical trial on postoperative pain and knee function
Authors' conclusion
iPACK block has no additional analgesic benefits for primary ACLR in the setting of a multimodal analgesia regimen including FTB and local infiltration analgesia.
Study context
- Population
- Patients scheduled for anterior cruciate ligament reconstruction (ACLR) under GA
- Participants
- 45 vs 45
- Comparison
- Femoral triangle block (FTB)+iPACK vs FTB alone
- FTBn = 45reference
- FTB+iPACKn = 45
- Primary endpoint
- Cumulative oral morphine equivalent (OME) consumption
- Follow-up
- First two postoperative days
Primary result
As reported in the abstract
Median of the difference
5 mg
95% CI −14 to 28
P = 0.49
By group
FTB+iPACK vs FTB
median of the difference 5 mg (95% CI −14 to 28); P = 0.49
Secondary outcomes
Pain scores and functional knee recovery (KOOS, International Knee Documentation Committee (IKDC), Lysholm) · 3, 6, and 9 months
- No significant intergroup differences
KOOS pain and symptoms subscales and IKDC by oral morphine equivalent (OME) consumption <50 mg in first two postoperative days · 9 months
- Higher with OME <50 mg, but differences did not reach the minimal clinically important difference
Safety
Opioid-related side effects
- No significant intergroup differences
Original publication
Comparison of femoral triangle plus iPACK blocks with femoral triangle block alone for anterior cruciate ligament reconstruction: a randomized controlled clinical trial on postoperative pain and knee function. Reg Anesth Pain Med. Published 7 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →