Paediatric anaesthesia & critical care

A Sedation Protocol for Endoscopic Baton‐Plate Adjustment in Neonates With Pierre Robin Sequence

Paediatr AnaesthPublished Retrospective cohort study

Authors' conclusion

Standardization of sedation protocols and procedural workflows was associated with shorter procedure times and fewer observed adverse events; however, the small sample size (n = 8 and n = 10) precludes conclusions regarding safety or causality.

Study context

Population
Neonates with Robin sequence undergoing endoscopic pre-epiglottic baton-plate (PEBP) adjustment, December 2012–June 2025
Participants
18 neonates
Exposure
Cohort I vs Cohort II
  • Cohort In = 8reference
  • Cohort IIn = 10
Outcome
Process characteristics and observed sedation-related adverse events
Methodological detailssingle-center, before-after comparison
  • Single-center
  • Before-after comparison

Main finding

As reported in the abstract

Sedation-related adverse events

Cohort I

4

events

Cohort II

1

events

Total sedation-related adverse events
5
Procedures completed successfully
18

Observational data: associations, not effects.

Further findings

Procedural duration

Significantly shorter in Cohort II

Baseline, lowest intraoperative and first postoperative SpO2

No significant difference

Safety

No patient required conversion to GA or invasive airway management

Original publication

A Sedation Protocol for Endoscopic Baton‐Plate Adjustment in Neonates With Pierre Robin Sequence. Paediatr Anaesth. Published 18 August 2026. doi:10.1002/pan.70286

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