Paediatric anaesthesia & critical care
A Sedation Protocol for Endoscopic Baton‐Plate Adjustment in Neonates With Pierre Robin Sequence
Authors' conclusion
Standardization of sedation protocols and procedural workflows was associated with shorter procedure times and fewer observed adverse events; however, the small sample size (n = 8 and n = 10) precludes conclusions regarding safety or causality.
Study context
- Population
- Neonates with Robin sequence undergoing endoscopic pre-epiglottic baton-plate (PEBP) adjustment, December 2012–June 2025
- Participants
- 18 neonates
- Exposure
- Cohort I vs Cohort II
- Cohort In = 8reference
- Cohort IIn = 10
- Outcome
- Process characteristics and observed sedation-related adverse events
Methodological detailssingle-center, before-after comparison
- Single-center
- Before-after comparison
Main finding
As reported in the abstract
Sedation-related adverse events
Cohort I
4
events
Cohort II
1
events
- Total sedation-related adverse events
- 5
- Procedures completed successfully
- 18
Observational data: associations, not effects.
Further findings
Procedural duration
- Significantly shorter in Cohort II
Baseline, lowest intraoperative and first postoperative SpO2
- No significant difference
Safety
- No patient required conversion to GA or invasive airway management
Original publication
A Sedation Protocol for Endoscopic Baton‐Plate Adjustment in Neonates With Pierre Robin Sequence. Paediatr Anaesth. Published 18 August 2026. doi:10. 1002/ pan. 70286
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