Pediatric anesthesia & critical care

A Single‐Center Descriptive Analysis of Interventions for Hypotension in Children: A Retrospective Cohort Study

Paediatr AnaesthPublished Retrospective cohort study

Authors' conclusion

Intervention rates in pediatric patients were lower than those reported in adults, with intervention thresholds decreasing with younger age. Use of intravascular volume expansion appears to be more commonly used to treat hypotension in infants compared to older children.

Study context

Population
Pediatric patients aged < 18 years undergoing noncardiac surgery under GA, 2015–2023anesthetic records analysed
Participants
37,958 patients
Exposure
Infants vs Preschool vs Children vs Teenagers
Outcome
Adjusted rate of intervention (any bolus of ephedrine, phenylephrine, epinephrine, norepinephrine, vasopressin, or 5% albumin); lowest MAP associated with an intervention
Methodological detailssingle-centre, observational
  • Single-centre
  • Observational

Main finding

As reported in the abstract

MAP associated with an intervention

Observational data: associations, not effects.

Further findings

Most commonly employed interventions

Most common intervention was 5% albumin, followed by phenylephrine

Original publication

A Single‐Center Descriptive Analysis of Interventions for Hypotension in Children: A Retrospective Cohort Study. Paediatr Anaesth. Published 11 August 2025. doi:10.1111/pan.70032

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