Cardiac arrest & resuscitation
A single center experience and outcomes with central and peripheral cannulations for paediatric extracorporeal cardiopulmonary resuscitation
Main finding · Survival to hospital discharge vs total resuscitation duration (CPA-ECMO, arrest to ECMO flow initiation)Result — go to the resultAdjusted OR of survival to hospital discharge 0.95 95% CI 0.92–0.99Authors' conclusion
In paediatric ECPR, total resuscitation duration remains a key metric associated with patient outcomes. In this single-center study, open peripheral cannulation is associated with more difficult and failed attempts compared to central cannulation.
Study context
- Population
- Patients < 18 years with in-hospital extracorporeal cardiopulmonary resuscitation (ECPR) events, 2015–2020
- Participants
- 92 ECPR events
- Exposure
- Central vs peripheral cannulation for paediatric ECPR
- Centraln = 40
- Peripheraln = 52reference
- Outcome
- Survival on hospital discharge
- Follow-up
- Hospital discharge
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Survival to hospital discharge vs total resuscitation duration (CPA-ECMO, arrest to ECMO flow initiation)
Adjusted OR of survival to hospital discharge
0.95
95% CI 0.92–0.99
P = 0.023
Central vs peripheral cannulation for paediatric ECPR
adjusted OR of survival to hospital discharge 0.95 (95% CI 0.92–0.99); P = 0.023
Observational data: associations, not effects.
Secondary outcomes
Total resuscitation duration (CPA-ECMO)
P = 0.12
Difficult cannulation
| Outcome | Central | Peripheral |
|---|---|---|
| Failure to achieve ECMO flows | — not stated in the abstract | 8/52 events |
— not stated in the abstract
- Failure to achieve ECMO flows — ECMO flows achieved overall
- 91% (84/92)
Favourable neurologic outcome vs total resuscitation duration (CPA-ECMO) · hospital discharge
- Adjusting for age or weight did not change the estimate
Failure to achieve ECMO flows
- Failure to achieve flows occurred exclusively with peripheral attempts
Original publication
A single center experience and outcomes with central and peripheral cannulations for paediatric extracorporeal cardiopulmonary resuscitation. Resuscitation. Published 13 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →