Cardiac arrest & resuscitation
Association between increasing institutional experience with ECPR and outcomes in patients with out-of-hospital cardiac arrest: A nationwide multicenter observational study in Japan (the JAAM–out-of-hospital cardiac arrest (OHCA) registry)
Authors' conclusion
Increasing institutional experience of ECPR did not significantly improve 30-day survival after OHCA but was associated with a shorter interval between hospital arrival and initiation of ECMO.
Study context
- Population
- Patients with OHCA in cardiac arrest on hospital arrival treated with extracorporeal membrane oxygenation (ECMO), JAAM-OHCA registry, Japan, June 2014–December 202087 facilities
- Participants
- 2,315 patients
- Exposure
- Increasing institutional ECPR experience
- Outcome
- 30-day survival
- Follow-up
- 30 days
Methodological detailsnationwide multicentre registry
- Nationwide multicentre registry
Main finding
As reported in the abstract
- 30-day survival not significantly associated with accumulated ECPR case volume
Observational data: associations, not effects.
Secondary outcomes
Interval between hospital arrival and ECMO initiation
- Decreased significantly with increasing ECPR experience
- P < 0.001
- Jonckheere-Terpstra test
30-day survival, non-shockable rhythm (subgroup)
- Tended to improve with increasing ECPR experience
- P = 0.04
- Cochran-Armitage trend test
- 1,268 non-shockable; 1,047 shockable
Original publication
Association between increasing institutional experience with ECPR and outcomes in patients with out-of-hospital cardiac arrest: A nationwide multicenter observational study in Japan (the JAAM–OHCA registry). Resuscitation. Published 3 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →