Cardiac arrest & resuscitation

Low-flow time and outcomes in hypothermic cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation: a secondary analysis of a multi-center retrospective cohort study

J Intensive CarePublished Secondary analysis of a multicentre retrospective cohort study

Authors' conclusion

OHCA patients with arrival body temperature < 32 °C who had received ECPR had relatively good survival outcomes regardless of low-flow time, in contrast to those of patients without AH.

Study context

Population
Adults (≥18 years) with out-of-hospital cardiac arrest (OHCA) admitted to the ED who underwent extracorporeal cardiopulmonary resuscitation (ECPR), Japan, January 2013–December 2018
Participants
1,252 eligible patients
Comparison
Accidental hypothermia (AH) vs non-AH, association of low-flow time with outcomes
  • AHn = 105
  • non-AHn = 1,147reference
Primary endpoint
Survival to discharge
Methodological detailsmulticentre registry
  • Multicentre registry

Primary result

As reported in the abstract

Significant interaction between low-flow time and AH in survival discharge rate
P for interaction = 0.048

Further findings

Low-flow time

Original publication

Low-flow time and outcomes in hypothermic cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation: a secondary analysis of a multi-center retrospective cohort study. J Intensive Care. Published 11 June 2024. doi:10.1186/s40560-024-00735-1

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.