Cardiac arrest & resuscitation
Association Between Rewarming Rate and Survival and Neurologic Outcome of Accidental Hypothermia
Primary result · 28-day survival (association with rewarming rate in the early phase)Result — go to the resultOR for 28-day survival per unit rewarming rate 1.51 95% CI 1.10–2.09Authors' conclusion
In the early phase, the rewarming rate was associated with survival and favorable neurologic outcomes.
Study context
- Population
- Adults with moderate-to-severe accidental hypothermia (body temperature <32°C on ED arrival), 36 emergency facilities in Japan, 2019–2022
- Comparison
- Rewarming rate in the early phase
- Primary endpoint
- 28-day survival after admission
- Follow-up
- 28 days
Methodological detailsnationwide, multicentre
- Nationwide
- Multicentre
Primary result
As reported in the abstract
28-day survival (association with rewarming rate in the early phase)
OR for 28-day survival per unit rewarming rate
1.51
95% CI 1.10–2.09
P = 0.011
Rewarming rate (early phase)
OR for 28-day survival per unit rewarming rate 1.51 (95% CI 1.10–2.09); P = 0.011
- Overall 28-day survival rate
- 82.0%
Secondary outcomes
Favourable neurologic status at discharge (Cerebral Performance Category 1-2)
| OR (95% CI) | P value | ||
|---|---|---|---|
| Rewarming rateMultivariable logistic regression | 1.32 (1.06–1.64) | P = 0.015 | |
| 0.512Odds ratio (log scale) |
- Favourable neurologic status at discharge (Cerebral Performance Category 1-2) — Overall proportion with favourable neurologic outcome (n = 263)
- 66.6%
Original publication
Association Between Rewarming Rate and Survival and Neurologic Outcome of Accidental Hypothermia. Crit Care Med. Published 3 June 2025. doi:10.
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