Cardiac arrest & resuscitation
Extracorporeal Cardiopulmonary Resuscitation in Hypothermic Cardiac Arrest: Severe Hypoglycemia Does Not Preclude Survival With Good Neurologic Outcome
Authors' conclusion
In patients with hypothermic cardiac arrest, severe hypoglycemia on admission to the hospital does not rule out survival with good neurologic outcomes after extracorporeal rewarming.
Study context
- Population
- Adults with accidental hypothermia (core temperature ≤28°C) and cardiac arrest undergoing extracorporeal rewarming, January 2014–June 2024
- Participants
- 127 adults
- Exposure
- Severe hypoglycaemia vs glucose ≥3 mmol/L
- Severe hypoglycemian = 21
- Outcome
- Survival to hospital discharge with favorable neurologic outcome
- Follow-up
- Hospital discharge
Methodological detailsmulticentre, registry-based (HELP Registry)
- Multicentre
- Registry-based (HELP Registry)
Main finding
As reported in the abstract
P = 0.7
- Lowest blood glucose in a survivor without neurologic deficit
- 0.9 mmol/L (16 mg/dL)
Observational data: associations, not effects.
Further findings
- Lowest blood glucose in a survivor without neurologic deficit (16 mg/dL)
- 0.9 mmol/L
Original publication
Extracorporeal Cardiopulmonary Resuscitation in Hypothermic Cardiac Arrest: Severe Hypoglycemia Does Not Preclude Survival With Good Neurologic Outcome. J Cardiothorac Vasc Anesth. Published 6 June 2025. doi:10. 1053/ j. jvca. 2025. 06. 006
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