Cardiac arrest & resuscitation

Extracorporeal Cardiopulmonary Resuscitation in Hypothermic Cardiac Arrest: Severe Hypoglycemia Does Not Preclude Survival With Good Neurologic Outcome

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

In patients with hypothermic cardiac arrest, severe hypoglycemia on admission to the hospital does not rule out survival with good neurologic outcomes after extracorporeal rewarming.

Study context

Population
Adults with accidental hypothermia (core temperature ≤28°C) and cardiac arrest undergoing extracorporeal rewarming, January 2014–June 2024
Participants
127 adults
Exposure
Severe hypoglycaemia vs glucose ≥3 mmol/L
  • Severe hypoglycemian = 21
Outcome
Survival to hospital discharge with favorable neurologic outcome
Follow-up
Hospital discharge
Methodological detailsmulticentre, registry-based (HELP Registry)
  • Multicentre
  • Registry-based (HELP Registry)

Main finding

As reported in the abstract

P = 0.7

Lowest blood glucose in a survivor without neurologic deficit
0.9 mmol/L (16 mg/dL)

Observational data: associations, not effects.

Further findings

Lowest blood glucose in a survivor without neurologic deficit (16 mg/dL)
0.9 mmol/L

Original publication

Extracorporeal Cardiopulmonary Resuscitation in Hypothermic Cardiac Arrest: Severe Hypoglycemia Does Not Preclude Survival With Good Neurologic Outcome. J Cardiothorac Vasc Anesth. Published 6 June 2025. doi:10.1053/j.jvca.2025.06.006

Composed by AI from the published abstract and checked against it. How Briefs are made →

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