Pediatric anesthesia & critical care
Accuracy and trending ability of non-invasive pulse-wave transit time-based cardiac output monitoring (esCCO) in critically ill children
Authors' conclusion
While esCCO demonstrated improved agreement with TTE following recalibration, its accuracy declined over time, highlighting the need for periodic recalibration to maintain reliability.
Study context
- Population
- Mechanically ventilated critically ill childrenmedian age 7.5 months
- Participants
- 50 participants
- Exposure
- esCCO vs TTE for cardiac index
- Outcome
- Agreement of Ci (bias, limits of agreement, percentage error) and trending ability
Methodological detailsmethod-comparison, Bland-Altman analysis, four-quadrant plot
- Method-comparison
- Bland-Altman analysis
- Four-quadrant plot
Main finding
As reported in the abstract
Agreement esCCO vs TTE
- T0 (demographic calibration): bias, L·min⁻¹·m⁻²
- + 5.9
- T0 limits of agreement, L·min⁻¹·m⁻²
- - 1.2 to + 13.1
- T0 percentage error
- 106.9%
- T1 (2 h post-recalibration): bias, L·min⁻¹·m⁻²
- + 0.1
- T1 limits of agreement
- - 1.0 to + 1.3
- T1 percentage error
- 12.7%
- T2 (18 h post-recalibration): bias
- + 0.2
- T2 limits of agreement
- - 1.7 to + 2.0
- T2 percentage error
- 20.7%
Observational data: associations, not effects.
Further findings
Trending ability (four-quadrant plot)
- Concordance rate (moderate trending ability)
- 79%
Original publication
Accuracy and trending ability of non-invasive pulse-wave transit time-based cardiac output monitoring (esCCO) in critically ill children. J Clin Monit Comput. Published 27 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →