Cardiac arrest & resuscitation
Accuracy of EEG Slow Wave Activity in Predicting Favorable Outcome in Patients With Hypoxic Brain Injury—A Protocol for a Substudy of the STEPCARE Trial
Study context
- Population
- Adult out-of-hospital cardiac arrest (OHCA) patients in the STEPCARE trialplanned recruitment 300
- Planned comparison
- C-Trend Index vs blinded retrospective visual analysis of cEEG
- Primary endpoint
- Accuracy (proportion of correct predictions of all predictions) in predicting favorable functional outcome (modified Rankin Scale 0-3); non-inferiority limit 2%
- Follow-up
- 6 months after cardiac arrest
Methodological detailspre-planned, non-inferiority, factorial parent trial, cEEG recorded starting as early as possible after ICU admission, Will assess whether the sedation intervention of STEPCARE modifies the performance of EEG-based predictors
- Pre-planned
- Non-inferiority
- Factorial parent trial
- cEEG recorded starting as early as possible after ICU admission
- Will assess whether the sedation intervention of STEPCARE modifies the performance of EEG-based predictors
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Accuracy of EEG Slow Wave Activity in Predicting Favorable Outcome in Patients With Hypoxic Brain Injury—A Protocol for a Substudy of the STEPCARE Trial. Acta Anaesthesiol Scand. Published 17 September 2025. doi:10. 1111/ aas. 70126
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