Acute respiratory distress syndrome and acute kidney injury in critically ill patients: A scoping review on this lung-kidney crosstalk
Authors' conclusion
This scoping review emphasizes the variability of the evidence, which hinders definitive conclusions about the association between ARDS and AKI, despite their common occurrence in critically ill patients.
Study context
- Population
- Critically ill patients with acute respiratory distress syndrome (ARDS) in hospitals; MEDLINE, Embase, LILACS to January 202428 studies
- Exposure
- ARDS-AKI vs ARDS only
- Outcome
- AKI development (mostly KDIGO criteria)
Methodological detailsJBI and PRISM-ScR methodology, 2943 studies screened
- JBI and PRISM-ScR methodology
- 2943 studies screened
Main finding
As reported in the abstract
Pooled overall rate of acute kidney injury (AKI) development across the studies
46.8%
95% CI 40.8–52.8
Observational data: associations, not effects.
Further findings
ARDS as independent risk factor for AKI
- ARDS identified as independent risk factor for AKI in 2 reports
Kidney replacement therapy and AKI recovery reporting
- Kidney replacement therapy described (studies)
- 17
- AKI recovery described (studies)
- 3
Hospital mortality
- Greater mortality risk in ARDS-AKI vs only ARDS (17 studies)
Original publication
Acute respiratory distress syndrome and acute kidney injury in critically ill patients: A scoping review on this lung-kidney crosstalk. J Crit Care. Published 27 January 2026. doi:10.
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