Perioperative medicine & outcomes
Adverse Effects Associated With Spinal Versus General Anaesthesia for Hip and Knee Arthroplasties: Protocol for a Systematic Review
Study context
- Population
- Adults undergoing hip or knee arthroplasty
- Planned comparison
- Spinal vs general anaesthesia
- Primary endpoint
- Proportion of participants with one or more serious adverse events
Methodological detailsPRISMA compliant, trial sequential analysis, RoB-2 risk of bias assessment, Grading of Recommendations, Assessment, Development and Evaluations (GRADE) certainty of evidence, Secondary outcomes: pain, postoperative opioid consumption, time to first mobilisation, hospital LOS, non-serious adverse events, quality of recovery
- PRISMA compliant
- Trial sequential analysis
- RoB-2 risk of bias assessment
- GRADE certainty of evidence
- Secondary outcomes: pain, postoperative opioid consumption, time to first mobilisation, hospital LOS, non-serious adverse events, quality of recovery
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Adverse Effects Associated With Spinal Versus General Anaesthesia for Hip and Knee Arthroplasties: Protocol for a Systematic Review. Acta Anaesthesiol Scand. Published 30 March 2026. doi:10.
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