Neuroanesthesia & neurocritical care
Adverse outcomes after surgery after a cerebrovascular accident or acute coronary syndrome: a retrospective observational cohort study
Main finding · CVA, ACS and AMI after elective surgeryResult — go to the resultAdjusted hazard ratio 2.12 95% CI 2.08–2.16Authors' conclusion
These observational data suggest increased adverse outcomes after a recent cardiovascular event can occur for up to 37 months after a major cardiovascular event.
Study context
- Population
- Adults undergoing noncardiac, non-neurologic surgery in NHS England, 2007–2018
- Participants
- 877,430 vs 20,582,717
- Exposure
- Prior cardiovascular event vs no event
- Previous cardiovascular eventn = 877,430
- Without an eventn = 20,582,717reference
- Outcome
- ACS, AMI or cerebrovascular accident (CVA) within 1 year of surgery (main exposure: time interval between preoperative cardiovascular event and surgery)
- Follow-up
- 1 year
Methodological detailslongitudinal, population-based, linked national data, Linked Hospital Episode Statistics (NHS England) and Myocardial Ischaemia National Audit Project data; multivariable logistic regression with restricted cubic splines, adjusted for age, sex, socioeconomic deprivation and comorbidities
- Longitudinal
- Population-based
- Linked national data
- Linked Hospital Episode Statistics (NHS England) and Myocardial Ischaemia National Audit Project data; multivariable logistic regression with restricted cubic splines, adjusted for age, sex, socioeconomic deprivation and comorbidities
Main finding
CVA, ACS and AMI after elective surgery
Adjusted hazard ratio
2.12
95% CI 2.08–2.16
Prior cardiovascular event vs Without an event
aHR 2.12 (95% CI 2.08–2.16)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aOR (95% CI) | |
|---|---|---|
| Prolonged hospital stay (major operations)Prior cardiovascular event vs Without an event | 1.36 (1.35–1.38) | |
| Unplanned readmission (major operations) · 30 daysPrior cardiovascular event vs Without an event | 1.28 (1.25–1.30) | |
| Unplanned readmission (major operations) · 1 yrPrior cardiovascular event vs Without an event | 1.60 (1.58–1.62) | |
| 0.512Adjusted odds ratio (log scale) |
Original publication
Adverse outcomes after surgery after a cerebrovascular accident or acute coronary syndrome: a retrospective observational cohort study. Br J Anaesth. Published 9 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →