Neuroanesthesia & neurocritical care
Risk of Mortality Following Surgery in Patients With a Previous Cardiovascular Event
Authors' conclusion
In this study, surgery within 1 year of an acute coronary syndrome or stroke was associated with increased postoperative mortality before reaching a new baseline, particularly for elective surgery.
Study context
- Population
- Adults undergoing NHS-funded noncardiac, nonneurologic surgery in England, April 1, 2007–March 31, 2018
- Participants
- 877,430 vs 20,582,717
- Exposure
- Prior cardiovascular event vs No prior cardiovascular event
- Prior cardiovascular eventn = 877,430
- No prior cardiovascular eventn = 20,582,717reference
- Outcome
- All-cause mortality
- Follow-up
- 30 days
Methodological detailslongitudinal, population-based, linked national registries, Data analysed July 2021 to July 2022
- Longitudinal
- Population-based
- Linked national registries
- Data analysed July 2021 to July 2022
Main finding
As reported in the abstract
Time interval after cardiovascular event associated with increased 30-day postoperative mortality
Increased risk with surgery within (months), all surgery
11.3
95% CI 10.8–11.7
Increased risk interval before elective surgery (months)
14.2
95% CI 13.3–15.3
Increased risk interval for emergency surgery (months)
7.3
95% CI 6.8–7.8
Observational data: associations, not effects.
Secondary outcomes
| Outcome | aHR (95% CI) | |
|---|---|---|
| 30-day mortality, emergency surgery (subgroup) | 1.35 (1.34–1.37) | |
| 30-day mortality, elective surgery (subgroup) | 1.83 (1.78–1.89) | |
| 0.512Adjusted hazard ratio (log scale) |
Original publication
Risk of Mortality Following Surgery in Patients With a Previous Cardiovascular Event. JAMA Surg. Published 1 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →