Airway management

Aerosol Box Use in Reducing Health Care Worker Contamination During Airway Procedures (AIRWAY Study)): A Simulation-Based Randomized Clinical Trial

JAMA Netw OpenPublished Randomised controlled trial

Authors' conclusion

In this randomized clinical trial of aerosol box use in AGMPs, use of an aerosol box reduced contamination deposition on HCPs' torso and face predoffing; the use of an aerosol box delayed time to successful intubation.

Study context

Population
Teams of 2 health care practitioner (HCPs) at tertiary care pediatric hospitals performing simulated bag-valve-mask ventilation, endotracheal intubation (ETI) and laryngeal mask airway (LMA) insertion122 analysed (61 teams)
Participants
128 participants
Comparison
Aerosol box vs no aerosol box during simulated aerosol-generating medical procedures (AGMPs)
Primary endpoint
Surface area of contamination (AOC) on participants
Methodological detailsmulticentre, simulation-based, Simulation; aerosols generated with Glo Germ; May to December 2021
  • Multicentre
  • Simulation-based
  • Simulation; aerosols generated with Glo Germ; May to December 2021

Primary result

As reported in the abstract

AOC on airway HCPs

Overall decreased area of contamination (AOC) to the torso

77.5%

95% CI −86.3% to −62.9%P < 0.001

Intervention

Overall decreased AOC to the facial area

60.7%

95% CI −75.2% to −37.8%P < 0.001

Intervention

Secondary outcomes

OutcomeMean difference (seconds) (95% CI)P value
Time to completing ETILonger with aerosol box10.2 (0.2–20.2)P = 0.04
Time to completing LMA insertion2.4 (−8.7 to 13.5)P = 0.67

Surface contamination after doffing PPE

No statistically significant difference between groups

Original publication

Aerosol Box Use in Reducing Health Care Worker Contamination During Airway Procedures (AIRWAY Study)): A Simulation-Based Randomized Clinical Trial. JAMA Netw Open. Published 3 April 2023. doi:10.1001/jamanetworkopen.2023.7894

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