Airway management

Influence of different airway devices on intra-arrest ventilation during bag-valve-device ventilation - a prospective randomized controlled cadaver study

Crit CarePublished Randomised controlled cadaver study

Primary result · ΔVtResult — go to the resultRegression coefficient −61.07 ml 95% CI −93.58 to −28.55

Authors' conclusion

The ∆Vt was lower in the ET group than the SGA group, whereas there was no evidence for differences in ∆Vt among the devices in the SGA group.

Study context

Population
Thiel-embalmed human cadavers in a standardized resuscitation scenario (mean age at death 84 ± 3.7 years)
Participants
11 cadavers
Comparison
ET vs SGA
Primary endpoint
Difference between Vtideal and Vte (∆Vt)
Methodological detailsprospective, randomized order of airway devices, Thiel-embalmed human cadavers, Chest compressions via Corpuls-CPR
  • Prospective
  • Randomized order of airway devices
  • Thiel-embalmed human cadavers
  • Chest compressions via Corpuls-CPR

Primary result

ΔVt

Regression coefficient

−61.07 ml

95% CI −93.58 to −28.55

P = 0.0003

Change by group

ET

142.2

mean · SD 125.5 · ml

SGA

202.0

mean · SD 153.1 · ml

As reported in the abstract

Further findings

Expiratory tidal volume (Vte)

regression coefficient (ml) 61.14 (28.63–93.65) · P = 0.0003

Leakage volume (Vleak)

regression coefficient (%) −20.98 (−26.63 to −15.33) · P < 0.0001

Mean pressure (Pmean)

regression coefficient (mbar) 0.90 (0.59–1.21) · P < 0.0001

Peak pressure (Ppeak)

regression coefficient (mbar) 11.46 (8.65–14.26) · P < 0.0001

ΔVt among SGA devices

No evidence for differences in ΔVt among the cadavers in the SGA group

Original publication

Influence of different airway devices on intra-arrest ventilation during bag-valve-device ventilation - a prospective randomized controlled cadaver study. Crit Care. Published 5 December 2025. doi:10.1186/s13054-025-05713-z

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