Cardiac arrest & resuscitation
Comparison of laryngeal tube evo with tracheal intubation during intra-arrest-ventilation using biphasic positive pressure ventilation - a prospective randomized controlled body donor study
Primary result · Expiratory tidal volume (VTe)Result — go to the resultDifference −295.7 ± 8 ml 95% CI −339.2 to −252.2Authors' conclusion
In this body donor model of biphasic-positive-airway-pressure-ventilation during mechanical cardiopulmonary resuscitation, TI provided higher VTe and lower leakage than LT®evo did. LT®evo ventilation frequently failed to achieve tidal volumes above the estimated dead space.
Study context
- Population
- Thiel-embalmed human body donors under mechanical CPR with biphasic positive airway pressure ventilationcrossover
- Participants
- 5 participants
- Comparison
- LT®evo vs TI
- Primary endpoint
- Expiratory tidal volume (VTe)
Methodological detailsprospective, Thiel-embalmed human body donors
- Prospective
- Thiel-embalmed human body donors
Primary result
As reported in the abstract
Difference
−295.7 ± 8 ml
95% CI −339.2 to −252.2
P < 0.0001
Secondary outcomes
| Outcome | Difference (ml/kg) (95% CI) | P value | |
|---|---|---|---|
| VTe per kg ideal body weight (VTe/kgIBW) | −5.0 (−5.7 to −4.2) | P < 0.0001 | |
| −10−505Difference, ml/kg (linear scale) |
| Outcome | Difference (mbar) (95% CI) | P value | |
|---|---|---|---|
| Peak pressure (PPeak) | −19.0 (−23.1 to −14.9) | P < 0.0001 | |
| Mean pressure (PMean) | −2 (−3.2 to −0.8) | P = 0.001 | |
| −30−20−10010Difference, mbar (linear scale) |
| Outcome | Difference (ml) (95% CI) | P value | |
|---|---|---|---|
| Delta tidal volume (ΔVT) | 296.0 (252.5–339.4) | P < 0.0001 | |
| −2000200400Difference, ml (linear scale) |
| Outcome | Difference (%) (95% CI) | P value | |
|---|---|---|---|
| Leakage volume (VLeak) | 52.7 (41.6–63.7) | P < 0.0001 | |
| −50050100Difference, % (linear scale) |
Successful ventilation (VTe/kgIBW > 2 ml/kg)
Original publication
Comparison of laryngeal tube evo with tracheal intubation during intra-arrest-ventilation using biphasic positive pressure ventilation - a prospective randomized controlled body donor study. Crit Care. Published 28 March 2026. doi:10.
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