Cardiac arrest & resuscitation
Ventilation parameters during Advanced Life Support in cardiac arrest (CAvent): A multicentre observational cohort study
Authors' conclusion
Ventilation parameters during CPR vary substantially across manual ventilation modes and airway modalities.
Study context
- Population
- Adults with cardiac arrest across five ALS systems in Sweden and the Netherlands28,120 ventilations analysed
- Participants
- 241 adults
- Exposure
- Ventilation modes (synchronous vs asynchronous) and airway modalities (bag-valve-mask (BVM), supraglottic airway device (SAD), endotracheal tube (ETT)) during CPR with manual ventilation
- Outcome
- Expiratory tidal volume
Methodological detailsmulticentre, mixed-effects regression models, May 2019 to August 2025, Ventilation parameters measured with a portable pneumotachograph and capnography device
- Multicentre
- Mixed-effects regression models
- May 2019 to August 2025
- Ventilation parameters measured with a portable pneumotachograph and capnography device
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
- Time of airway pressure >30 cmH2O — Asynchronous ETT
- 5.8 (95% CI 5.1–6.4) s·min-1
- Peak inspiratory pressure — Asynchronous ETT
- 51.0 (95% CI 48.7–53.1) cmH2O
Time of airway pressure >30 cmH2O
- Longest with asynchronous ETT ventilation
Peak inspiratory pressure
- Highest with asynchronous ETT ventilation
Original publication
Ventilation parameters during Advanced Life Support in cardiac arrest (CAvent): A multicentre observational cohort study. Resuscitation. Published 14 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →