Cardiac arrest & resuscitation
Aetiology and predictors of outcome in non‐shockable in‐hospital cardiac arrest: A retrospective cohort study from the Swedish Registry for Cardiopulmonary Resuscitation
Main finding · Survival to hospital dischargeResult — go to the resultAbsolute difference 7.3% 95% CI 5.2%–9.4%Authors' conclusion
Asystole was associated with higher survival compared to PEA, possibly due to shorter CPR durations and a larger proportion of reversible aetiologies.
Study context
- Population
- Adult non-shockable In-hospital Cardiac Arrest (IHCA) cases, Swedish Registry of Cardiopulmonary Resuscitation, 2018 to 2022
- Participants
- 5,788 cases
- Exposure
- Initial asystole vs pulseless electrical activity (PEA) in non-shockable IHCA
- Asystolen = 3,086
- PEAn = 2,702reference
- Outcome
- Survival to hospital discharge
Methodological detailsnationwide registry, random forest model
- Nationwide registry
- Random forest model
Main finding
As reported in the abstract
Absolute difference
7.3%
95% CI 5.2%–9.4%
By group
Asystole vs PEA
absolute difference 7.3% (95% CI 5.2%–9.4%)
Observational data: associations, not effects.
Further findings
| Outcome | Asystole | PEA | Absolute difference (95% CI) | |
|---|---|---|---|---|
| Aetiology: cardiac ischemiaMost frequent aetiology in both PEA and asystole | 19% | 24% | 5.4% (3.0%–7.7%) | |
| −50510Difference (linear scale) |
Aetiology: respiratory failure
min
| Outcome | Asystole | PEA | Absolute difference (min) (95% CI) | |
|---|---|---|---|---|
| CPR duration | 15 | 18 | 4.9 (4.0–5.9) | |
| −50510Difference, min (linear scale) |
Aetiology: respiratory failure
- No significant difference
Predictors of survival (random forest variable importance)
- Cardiopulmonary resuscitation (CPR) duration the single most important predictor of survival across all subgroup and sensitivity analyses
- Aetiology second most important predictor in most analyses, except asystole subgroup where responsiveness at cardiac arrest team arrival took precedence
Original publication
Aetiology and predictors of outcome in non‐shockable in‐hospital cardiac arrest: A retrospective cohort study from the Swedish Registry for Cardiopulmonary Resuscitation. Acta Anaesthesiol Scand. Published 11 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →