ICU sedation, delirium & recovery
Age-related sex differences in intensive care treatment and outcomes: a nationwide cohort study
Main finding · 30-day mortalityResult — go to the resultOdds ratio 1.03 CI 1.01–1.05Authors' conclusion
Although males constitute a larger proportion of ICU patients and receive more advanced treatments, females have higher adjusted mortality.
Study context
- Population
- Adult (≥18 yr) ICU patients, Swedish Intensive Care Registry, 2012–202442.8% female
- Participants
- 303,875 participants
- Exposure
- Female vs male ICU patients
- Outcome
- 30-day mortality
- Follow-up
- 30 days
Methodological detailsnationwide registry, multivariable logistic regression, natural cubic splines (age–sex interaction)
- Nationwide registry
- Multivariable logistic regression
- Natural cubic splines (age–sex interaction)
Main finding
As reported in the abstract
Odds ratio
1.03
CI 1.01–1.05
Female vs Male
OR 1.03 (CI 1.01–1.05)
Observational data: associations, not effects.
Further findings
| Outcome | OR (CI) | |
|---|---|---|
| Crude mortalityCrude mortality higher in male patients | 0.94 (0.92–0.95) | |
| 0.512Odds ratio (log scale) |
Continuous RRT and invasive ventilation
- Male patients more likely to receive continuous RRT and invasive ventilation
Mortality by age (age–sex interaction)
- Female patients had lower mortality risk at younger ages and higher mortality risk at older ages
Original publication
Age-related sex differences in intensive care treatment and outcomes: a nationwide cohort study. Br J Anaesth. Published 29 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →