Cardiac arrest & resuscitation
Age, sex, and survival following ventricular fibrillation cardiac arrest: A mechanistic evaluation of the ECG waveform
Main finding · Survival to hospital dischargeResult — go to the resultOdds ratio 1.93 95% CI 1.23–3.09Authors' conclusion
Women <55 years were more likely to survive than men <55 years following VF-OHCA. The biologic mechanism represented by VF waveform mediated some, though not all, of the outcome difference.
Study context
- Population
- VF-OHCA patients in a metropolitan EMS system29% female
- Participants
- 1,526 patients
- Exposure
- Women vs men, by age group
- Outcome
- Survival to hospital discharge
Methodological detailsmetropolitan EMS system, mediation analysis
- Metropolitan EMS system
- Mediation analysis
Main finding
As reported in the abstract
Odds ratio
1.93
95% CI 1.23–3.09
By group
Women <55 vs Men <55
OR 1.93 (95% CI 1.23–3.09)
Observational data: associations, not effects.
Further findings
Proportion of survival benefit (female sex, <55 years) mediated by ventricular fibrillation (VF) waveform measures
- Mediated by VitalityScore
- 47%
- Mediated by amplitude spectrum area (AMSA) (amplitude spectrum area)
- 25%
- Waveform measures more favourable among women
Original publication
Age, sex, and survival following ventricular fibrillation cardiac arrest: A mechanistic evaluation of the ECG waveform. Resuscitation. Published 28 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →