Cardiac arrest & resuscitation

Artificial intelligence (AI)-driven carotid artery compressibility assessment via point-of-care ultrasound for blood pressure estimation in critically ill and post-resuscitation patients: a prospective observational study

Crit CarePublished Prospective observational study

Authors' conclusion

This proof-of-concept study demonstrated potential diagnostic utility of carotid artery compressibility for blood pressure estimation in critically ill and post-ROSC patients with hypotensive conditions.

Study context

Population
Critically ill and post-ROSC patients in the ED372 ultrasound clips
Participants
56 participants
Exposure
AI-quantified carotid artery compressibility (CAC) on point-of-care ultrasound (POCUS) vs concurrently measured blood pressure (BP)
Outcome
Diagnostic performance of the model for identifying hypotension
Methodological detailsdiagnostic and regression analyses, AI-derived (deep learning, RealCAC-Net)
  • Diagnostic and regression analyses
  • AI-derived (deep learning, RealCAC-Net)

Main finding

As reported in the abstract

AUC for SBP < 60 mmHg

0.90

95% CI 0.87–0.93

AUC for mean BP < 40 mmHg

0.91

95% CI 0.88–0.94

Observational data: associations, not effects.

Further findings

Continuous BP estimation (regression models)

Root mean squared errors as low as (mmHg)
8.3
Model performed best in hypotensive ranges

Original publication

AI-driven carotid artery compressibility assessment via point-of-care ultrasound for blood pressure estimation in critically ill and post-resuscitation patients: a prospective observational study. Crit Care. Published 28 November 2025. doi:10.1186/s13054-025-05772-2

Composed by AI from the published abstract and checked against it. How Briefs are made →

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