Cardiac arrest & resuscitation
Alveolar Ventilation Efficiency Assessed via Capnography is Associated with Improved Outcomes in Pediatric Cardiac Arrest
Main finding · Survival to hospital dischargeResult — go to the resultAdjusted relative risk 1.53 95% CI 1.03–2.28Authors' conclusion
In this multicenter study, an AOI ≥0.35 was associated with improved survival outcomes.
Study context
- Population
- Children (≤18 years) with invasive airways and capnography data during cardiopulmonary resuscitation (CPR)
- Participants
- 99 events
- Exposure
- Event-level average airway opening index (AOI) ≥0.35 vs <0.35
- Outcome
- Survival to hospital discharge
Methodological detailsmulticentre, observational, sensitivity analysis excluding E-CPR
- Multicentre
- Observational
- Sensitivity analysis excluding E-CPR
Main finding
As reported in the abstract
Adjusted relative risk
1.53
95% CI 1.03–2.28
P = 0.04
AOI ≥0.35 vs AOI <0.35
aRR 1.53 (95% CI 1.03–2.28); P = 0.04
Observational data: associations, not effects.
Further findings
| Outcome | aRR (95% CI) | P value | |
|---|---|---|---|
| Favorable neurological outcome | 1.56 (1.01–2.41) | P = 0.04 | |
| 0.512Adjusted relative risk (log scale) |
Peak arterial lactate after return of circulation
P = 0.006
CPR duration
P = 0.64
AOI during pediatric CPR (all events)
- Median AOI
- 0.38 [0.25, 0.53]
Original publication
Alveolar Ventilation Efficiency Assessed via Capnography is Associated with Improved Outcomes in Pediatric Cardiac Arrest. Am J Respir Crit Care Med. Published 19 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →