Cardiac arrest & resuscitation
Associations between perfusion index during out-of-hospital cardiopulmonary resuscitation, cardiopulmonary resuscitation quality and return of spontaneous circulation
Authors' conclusion
Cycle-average PI was positively correlated with chest compression fraction while higher event-average PI was associated with higher probability of unadjusted and adjusted sustained return of spontaneous circulation but not with neurological intact survival.
Study context
- Population
- Index out-of-hospital cardiac arrests attended January 2022 through October 2024
- Participants
- 98 arrests
- Exposure
- Event-average perfusion index during CPR, by sustained ROSC
- Outcome
- Association of event-average PI with sustained return of spontaneous circulation
Main finding
As reported in the abstract
Sustained return of spontaneous circulation (ROSC)
- Events with sustained return of spontaneous circulation had a higher event-average perfusion index (PI): median 0.92 [Q1, Q3 0.44, 1.73] mmol/L vs 0.19 [0.09, 0.55]
- P < 0.001
- PI as predictor of sustained ROSC, AUC (95% CI 0.68-0.86); optimal cut point 0.61, sensitivity 0.67, specificity 0.81
- 0.77
Observational data: associations, not effects.
Further findings
Survival to hospital admission
| Adjusted OR (95% CI) | P value | ||
|---|---|---|---|
| Event-average PI | 2.1 (1.2–3.7) | P = 0.001 | |
| 0.20.5125Adjusted odds ratio (log scale) |
Neurologically intact survival
| Adjusted OR (95% CI) | P value | ||
|---|---|---|---|
| Event-average PINot associated | 4.0 (0.8–19.4) | P = 0.085 | |
| 0.050.21520Adjusted odds ratio (log scale) |
Cycle-average PI and chest compression fraction
- Higher cycle-average PI independently associated with higher chest compression fraction
- P = 0.003
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Associations between perfusion index during out-of-hospital cardiopulmonary resuscitation, cardiopulmonary resuscitation quality and return of spontaneous circulation. Resuscitation. Published 1 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →