Cardiac arrest & resuscitation

Diastolic blood pressures and end tidal carbon dioxides during cardiopulmonary resuscitations and their association with outcomes in adult out-of-hospital cardiac arrest patients: A preplanned secondary analysis of the Augmented Medication CardioPulmonary resuscitation (AMCPR) trial

ResuscitationPublished Secondary analysis of the AMCPR randomised trial

Authors' conclusion

Monitoring DBP during resuscitation in patients with cardiac arrest may provide additional information about successful initial resuscitation.

Study context

Population
Adults with OHCA
Participants
264 adults
Comparison
Diastolic blood pressure (DBP) and ETCO2 during cardiopulmonary resuscitation (CPR) in patients with vs without sustained return of spontaneous circulation (ROSC)
  • Sustained ROSCn = 101
Primary endpoint
Sustained ROSC (≥20 min)
Methodological detailspreplanned
  • Preplanned

Primary result

As reported in the abstract

Independently associated
AOR for sustained ROSC (95% CI)P value
Follow-up DBP above 26.5
10.03(3.64–27.66)
P < 0.01
Delta DBP above 6.5
4.83(1.90–12.26)
P < 0.01
Sustained ROSC achieved
101 (38.3%)

Original publication

Diastolic blood pressures and end tidal carbon dioxides during cardiopulmonary resuscitations and their association with outcomes in adult out-of-hospital cardiac arrest patients: A preplanned secondary analysis of the Augmented Medication CardioPulmonary resuscitation (AMCPR) trial. Resuscitation. Published 12 February 2025. doi:10.1016/j.resuscitation.2025.110537

Composed by AI from the published abstract and checked against it. How Briefs are made →

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