Cardiac arrest & resuscitation
Diastolic blood pressure and end-tidal carbon dioxide during adult ICU cardiopulmonary resuscitation: association with return of spontaneous circulation
Authors' conclusion
In adult ICU cardiac arrest events with simultaneous arterial pressure and capnographic monitoring, both DBP and EtCO2 were associated with ROSC. DBP showed numerically higher discrimination than EtCO2, although this was not statistically significant for mean values across the CPR episode.
Study context
- Population
- Adult patients with cardiac arrest in a medical-surgical ICU with an indwelling arterial catheter and mainstream capnographyevents from 63 patients
- Participants
- 68 patients
- Exposure
- Events achieving ROSC vs events without ROSC
- ROSCn = 29
- Outcome
- ROSC (association with mean DBP and mean EtCO2 across the CPR episode)
Methodological detailssingle-centre, Conducted over 9 months, diastolic blood pressure (DBP) and EtCO2 recorded at end of each 2-min CPR cycle; logistic regression and ROC analysis
- Single-centre
- Conducted over 9 months
- DBP and EtCO2 recorded at end of each 2-min CPR cycle; logistic regression and ROC analysis
Main finding
As reported in the abstract
Mean DBP across the CPR episode
Mean difference, mmHg (95% CI)P value
ROSC vs No ROSC
15(8–23)
P < 0.001- DBP vs EtCO2 · mean values; difference not statistically significant
- AUC 0.78 vs 0.69; DeLong p = 0.30
Observational data: associations, not effects.
Further findings
Mean, mmHg
| Outcome | ROSC | No ROSC | Mean difference (mmHg) (95% CI) | P value | |
|---|---|---|---|---|---|
| Mean EtCO2 across the CPR episode | 19 (SD 5) | 15 (SD 6) | 4 (1–6) | P = 0.010 | |
| −50510Difference, mmHg (linear scale) |
| Outcome | AUC | P value |
|---|---|---|
| Last recorded pre-outcome values (secondary peri-outcome analysis)DBP vs EtCO2 | 0.96 vs 0.85 | DeLong p = 0.04 |
- Last recorded pre-outcome values (secondary peri-outcome analysis): time point identifiable only after ROSC or termination of resuscitation
Original publication
Diastolic blood pressure and end-tidal carbon dioxide during adult ICU cardiopulmonary resuscitation: association with return of spontaneous circulation. Resuscitation. Published 22 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →